Save Money on Prescriptions. Choosing a generic drug over a brand name can save you lots of money — depending on what you take, you could enjoy a 52% cut in the daily cost of medications, reports the FDA. But now there’s another reason to go generic: Fill your Rx at one of the big-box retailers like Wal-Mart, Target, or Kmart, and you can get a month’s supply for as little as $4 or a 90-day supply for $10 to $15 (Ref. Kameleon007/istock).